![]() One of the clear differences between IMO and SIBO is how the body’s digestive symptoms change. This will lead to a lot of flatulence, eructation, and trips to the bathroom as the bacteria break down their meal and expel their byproducts into our digestive systems. When a meal is finally present, the starving bacteria are going to consume it quickly and stuff themselves. If you have a mutation in the FUT2 gene you don’t secrete your blood type sugars and hence the bacteria don’t get a free meal on a regular basis. This is why certain probiotics work better (in my opinion) than others. These bacteria, like everyone else, like a free meal. This sugar is then consumed by the normal commensal bacteria that live there. This gene secretors blood type antigens ie your blood type sugar inside the digestive tract. This is a result of a gene mutation called FUT2. This sugar is also found in high abundance in 80% of people’s digestive tracts. Since your blood type is just a carbohydrate aka sugar this sugar can be located throughout your body (not just on your red blood cells) and on the foods that you eat. All of which leads to the classic symptoms of IMO. This in combination with the list factors listed in the paragram above will cause IMO. This methane gas (CH4) causes damage to some of the nerves in the intestines which further reduces transit time/motility which in turn causes more damage and symptoms. This organism we now understand takes hydrogen gas (H2) from Ruminococcus and Chrisensenella organisms and consumes it to make its methane gas. The main organism in the human body that causes IMO is Methanobrevibacter smithii. IMO organisms create methane gas as a byproduct. This fermentation of these carbohydrates is going to cause damage to the intestinal tract cells causing a “leaky gut” or a malabsorption syndrome. and thus these carbohydrates are going to ferment. ![]() When there is an overabundance of carbohydrates in the intestines that are not absorbed into our body these microorganisms are going to consume these carbohydrates. Archaea, like bacteria, like to eat carbohydrates. This could be food rotting in the stomach, food not being removed from the body, or numerous other issues listed below. Because food is not breaking down properly in the digestive tract, it causes a number of digestion issues as the body processes. The high levels of archaea in the intestines can cause malabsorption, preventing the body from properly utilizing nutrients. ![]() Medications such as antibiotics and medications that suppress stomach acid production such as proton pump inhibitors and H2 blockers (2). Other diseases such as Liver and kidney diseases, pancreatitis, Crohn’s disease, celiac disease, malnutrition. The elderly population has an increased risk. Metabolic diseases such as Type 2 Diabetes Mellitus, or hypochlorhydria or low stomach acid. Motility disorders of the digestive tract as a result of gastroparesis, Celiac disease (CeD), or other diseases that can affect the migrating motor complex (MMC). Other risk factors that can cause SIBO are: Anatomical/structure pathologies inside the intestinal tract like diverticula, strictures, blind loops like short bowel syndrome (SBS), adhesions from abdominal surgery, and fistulas (more common in Inflammatory Bowel diseases). It turns out that about 70% of IBS sufferers actually have IMO/SIBO (1). While we don’t have much statistical evidence on the prevalence of IMO/SIBO we do have a fair amount on IBS. This is because IBS is a diagnosis of exclusion, meaning that the doctor couldn’t find a cause for the patient’s digestive complaints. Individuals who have a diagnosis of IBS are more likely to have IMO. While anyone can have IMO, research has found some groups of people have a higher predisposition than others. However, it did not take into account organisms that are not bacteria and can be located throughout the digestive tract, not just isolated to the small bowels. In the past, the diagnosis of SIBO or Small Intestinal Bacterial Overgrowth was used as a blanket diagnosis. Naturopathic Physicians have been treating digestive issues for years but a specific name was not agreed upon until recently. These pesty microorganisms can cause a host of digestive symptoms that often go undiagnosed or wrongly diagnosed as Irritable Bowel Syndrome without diarrhea (IBS-c) among other diagnoses. Intestinal Methanogen Overgrowth, or IMO (E-Mo), is when methane-producing archaea are found in the intestines. Lupus (SLE) Natural Treatments that work.Small Intestinal Fungal Overgrowth (SIFO).Small Intestinal Bacterial Overgrowth (SIBO).Acupuncture and Inflammatory Bowel Disease (IBD).Acupuncture and Acupoints: A Brief Summary.
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